Anti-GNA11 Polyclonal Antibody
Cat: K003471P
Summary:
| 【Product name】：Anti-GNA11 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2767 | 【Swiss Prot】：P29992 |
| 【Species reactivity】：Mouse,Human,Rat | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：Recombinant protein of human GNA11 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
Verified picture:
Western blot analysis with GNA11 antibody diluted at 1:1000
Immunohistochemistry of paraffin-embedded human esophageal cancer with GNA11 antibody diluted at 1:100.