Anti-GEMIN2 Polyclonal Antibody
Cat: K003584P
Summary:
| 【Product name】：Anti-GEMIN2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8487 | 【Swiss Prot】：O14893 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human GEMIN2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Verified picture:
Western blot analysis with GEMIN2 antibody diluted at 1:700;Lane: Jurkat.
Immunohistochemistry of paraffin-embedded rat liver using GEMIN2 antibody at dilution of 1:200.