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Anti-EPHB4 Polyclonal Antibody
Cat: K003647P
Summary:
【Product name】:Anti-EPHB4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:2050 【Swiss Prot】:P54760
【Species reactivity】:Mouse,Human
【Tested applications】:WB
【Immunogen】:Recombinant protein of human EPHB4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Verified picture:
Western blot analysis with EPHB4 antibody diluted at 1:1000;Lane: Mouse liver.