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Anti-UBE4A Polyclonal Antibody
Cat: K003658P
Summary:
【Product name】:Anti-UBE4A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:9354 【Swiss Prot】:Q14139
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human UBE4A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Western blot analysis with UBE4A antibody diluted at 1:1000;Lane: MCF7 HepG2 293T Mouse kidney Mouse pancreas Mouse liver.
Immunohistochemistry of paraffin-embedded rat brain with UBE4A antibody diluted at 1:100.