Anti-UBE4A Polyclonal Antibody - HRP
Cat: K003658P - HRP
Summary:
| 【Product name】：Anti-UBE4A Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9354 | 【Swiss Prot】：Q14139 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human UBE4A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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