Anti-GUCY2D Polyclonal Antibody
Cat: K003679P
Summary:
| 【Product name】：Anti-GUCY2D Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3000 | 【Swiss Prot】：Q02846 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human GUCY2D | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Verified picture:
Western blot analysis with GUCY2D antibody diluted at 1:1000;Lane: Mouse brain Mouse spinal cord Mouse kidney.