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Anti-GUCY2D Polyclonal Antibody - SAlexa Fluor 647
Cat: K003679P - SAlexa Fluor 647
Summary:
【Product name】:Anti-GUCY2D Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3000 【Swiss Prot】:Q02846
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human GUCY2D
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
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