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Anti-ATP6V1E1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K003694P - SAlexa Fluor 405
Summary:
【Product name】:Anti-ATP6V1E1 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:529 【Swiss Prot】:P36543
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IF,WB
【Immunogen】:Recombinant protein of human ATP6V1E1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.
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