Anti-GCLM Polyclonal Antibody
Cat: K003905P
Summary:
| 【Product name】：Anti-GCLM Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2730 | 【Swiss Prot】：P48507 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human GCLM | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with GCLM antibody diluted at 1:1000;Lane: HeLa Mouse liver Mouse spleen Mouse kidney Rat kidney.
Immunofluorescence analysis of PC-12 cells using GCLM antibody diluted at 1:100.