Anti-PFKM Polyclonal Antibody - SAlexa Fluor 640
Cat: K004024P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-PFKM Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5213 | 【Swiss Prot】：P08237 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human PFKM | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
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