Anti-ATIC Polyclonal Antibody
Cat: K004063P
Summary:
| 【Product name】：Anti-ATIC Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：471 | 【Swiss Prot】：P31939 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human ATIC | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Verified picture:
Western blot analysis with ATIC antibody diluted at 1:1000;Lane: MCF7 SW480 NCI-H460 HepG2 SW620 HT-29 K-562.