Anti-PIAS1 Polyclonal Antibody
Cat: K004168P
Summary:
| 【Product name】：Anti-PIAS1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8554 | 【Swiss Prot】：O75925 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IF | |
| 【Immunogen】：Recombinant protein of human PIAS1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Verified picture:
Immunofluorescence analysis of U2OS cell using PIAS1 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of GFP-RNF168 transgenic U2OS cells using PIAS1 antibody diluted at 1:100.