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Anti-HDAC8 Polyclonal Antibody - SAlexa Fluor 350
Cat: K004238P - SAlexa Fluor 350
Summary:
【Product name】:Anti-HDAC8 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:55869 【Swiss Prot】:Q9BY41
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human HDAC8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
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