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Anti-CELF1 Polyclonal Antibody - RBITC
Cat: K004308P - RBITC
Summary:
【Product name】:Anti-CELF1 Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:10658 【Swiss Prot】:Q92879
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CELF1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
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