下载
Anti-NEU1 Polyclonal Antibody - SAlexa Fluor 555
Cat: K004418P - SAlexa Fluor 555
Summary:
【Product name】:Anti-NEU1 Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4758 【Swiss Prot】:Q99519
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human NEU1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
Verified picture: