Anti-PCBD1 Polyclonal Antibody
Cat: K004487P
Summary:
| 【Product name】：Anti-PCBD1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5092 | 【Swiss Prot】：P61457 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human PCBD1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunofluorescence analysis of U2OS cell using PCBD1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with PCBD1 antibody diluted at 1:1000;Lane: SW620 Mouse liver Mouse kidney Mouse pancreas Rat liver.
Immunofluorescence analysis of MCF7 cells using PCBD1 antibody diluted at 1:50.