Anti-GAMT Polyclonal Antibody
Cat: K004645P
Summary:
| 【Product name】：Anti-GAMT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2593 | 【Swiss Prot】：Q14353 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human GAMT | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
Verified picture:
Immunofluorescence analysis of U20S cell using GAMT antibody. Blue: DAPI for nuclear staining.
Western blot analysis with GAMT antibody diluted at 1:1000;Lane: HepG2 Jurkat HeLa 293T Mouse liver Rat liver Rat brain.
Immunohistochemistry of paraffin-embedded human liver with GAMT antibody diluted at 1:100.
Immunofluorescence analysis of A549 cells using GAMT antibody diluted at 1:100.