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Anti-PCMT1 Polyclonal Antibody
Cat: K004711P
Summary:
【Product name】:Anti-PCMT1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5110 【Swiss Prot】:P22061
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:IP,IF,WB
【Immunogen】:Recombinant protein of human PCMT1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Western blot analysis with PCMT1 antibody diluted at 1:1000;Lane: MCF7 HepG2 293T A431 Mouse liver Mouse brain Rat brain Rat heart Rat heart.
Immunohistochemistry of paraffin-embedded Ovarian cancer(hu) using PCMT1 antibody at dilution of 1:100 (x100 lens,x200 lens).
Immunofluorescence analysis of HeLa cell using PCMT1 antibody. Blue: DAPI for nuclear staining.