Anti-RTKN Polyclonal Antibody
Cat: K004751P
Summary:
| 【Product name】：Anti-RTKN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6242 | 【Swiss Prot】：Q9BST9 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human RTKN | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunofluorescence analysis of MCF7 cell using RTKN antibody. Blue: DAPI for nuclear staining.
Western blot analysis with RTKN antibody diluted at 1:1000;Lane: A431 HepG2 MCF7.
Immunofluorescence analysis of C6 cells using RTKN antibody diluted at 1:100.