Anti-BMP3 Polyclonal Antibody
Cat: K004836P
Summary:
| 【Product name】：Anti-BMP3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：651 | 【Swiss Prot】：P12645 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human BMP3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
Verified picture:
Western blot analysis with BMP3 antibody diluted at 1:1000;Lane: SW480 Mouse ovary Mouse lung.
Immunohistochemistry of paraffin-embedded rat kidney using BMP3 antibody at dilution of 1:100 (x40 lens).