Anti-BMP3 Polyclonal Antibody - Biotin
Cat: K004836P - Biotin
Summary:
| 【Product name】：Anti-BMP3 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：651 | 【Swiss Prot】：P12645 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human BMP3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
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