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Anti-BMP3 Polyclonal Antibody - SAlexa Fluor 640
Cat: K004836P - SAlexa Fluor 640
Summary:
【Product name】:Anti-BMP3 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:651 【Swiss Prot】:P12645
【Species reactivity】:Rat,Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human BMP3
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
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