Anti-PDE6B Polyclonal Antibody - SAlexa Fluor 555
Cat: K004881P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-PDE6B Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5158 | 【Swiss Prot】：P35913 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PDE6B | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
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