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Anti-PRC1 Polyclonal Antibody
Cat: K004952P
Summary:
【Product name】:Anti-PRC1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:9055 【Swiss Prot】:O43663
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human PRC1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with PRC1 antibody diluted at 1:1000;Lane: MCF7 Jurkat 293T HepG2.
Immunohistochemistry of paraffin-embedded rat spleen with PRC1 antibody diluted at 1:100.
Immunofluorescence analysis of MCF7 cells using PRC1 antibody diluted at 1:100.