Anti-ELAC2 Polyclonal Antibody - RBITC
Cat: K005034P - RBITC
Summary:
| 【Product name】：Anti-ELAC2 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：60528 | 【Swiss Prot】：Q9BQ52 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ELAC2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
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