Anti-RNF7 Polyclonal Antibody - FITC
Cat: K005154P - FITC
Summary:
| 【Product name】：Anti-RNF7 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9616 | 【Swiss Prot】：Q9UBF6 |
| 【Species reactivity】：Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RNF7 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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