Anti-RUNX3 Polyclonal Antibody
Cat: K005156P
Summary:
| 【Product name】：Anti-RUNX3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：864 | 【Swiss Prot】：Q13761 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human RUNX3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with RUNX3 antibody diluted at 1:1000;Lane: Mouse stomach.
Immunofluorescence analysis of MCF7 cell using RUNX3 antibody. Blue: DAPI for nuclear staining.