Anti-XRCC6 Polyclonal Antibody
Cat: K005178P
Summary:
| 【Product name】：Anti-XRCC6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2547 | 【Swiss Prot】：P12956 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IP,IF,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human XRCC6 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Verified picture:
Immunofluorescence analysis of A549 cell using XRCC6 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with XRCC6 antibody diluted at 1:1000;Lane: COS-7 SW480 Mouse brain.
Immunohistochemistry of paraffin-embedded rat brain with XRCC6 antibody diluted at 1:75.