Anti-MAP3K20 Polyclonal Antibody
Cat: K005212P
Summary:
| 【Product name】：Anti-MAP3K20 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：51776 | 【Swiss Prot】：Q9NYL2 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human MAP3K20 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Verified picture:
Western blot analysis with MAP3K20 antibody diluted at 1:1000;Lane: MCF7 A549 HepG2 Mouse lung Mouse heart Rat brain.
Immunohistochemistry of paraffin-embedded human colon carcinoma tissue using ZAK antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of A549 cell using ZAK antibody. Blue: DAPI for nuclear staining.