Anti-ASPSCR1 Polyclonal Antibody
Cat: K005278P
Summary:
| 【Product name】：Anti-ASPSCR1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：79058 | 【Swiss Prot】：Q9BZE9 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IP,IF,WB | |
| 【Immunogen】：Recombinant protein of human ASPSCR1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
Verified picture:
Immunofluorescence analysis of A549 cell using ASPSCR1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with ASPSCR1 antibody diluted at 1:1000;Lane: 293T SW480 A549 BT-474 Mouse liver Mouse testis.
Immunofluorescence analysis of HeLa cells using ASPSCR1 antibody diluted at 1:100.