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Anti-LOX Polyclonal Antibody - SAlexa Fluor 647
Cat: K005397P - SAlexa Fluor 647
Summary:
【Product name】:Anti-LOX Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4015 【Swiss Prot】:P28300
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human LOX
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
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