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Anti-FLNA Polyclonal Antibody - SAlexa Fluor 555
Cat: K005538P - SAlexa Fluor 555
Summary:
【Product name】:Anti-FLNA Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:2316 【Swiss Prot】:P21333
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human FLNA
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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