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Anti-RGR Polyclonal Antibody
Cat: K005559P
Summary:
【Product name】:Anti-RGR Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5995 【Swiss Prot】:P47804
【Species reactivity】:Rat
【Tested applications】:WB
【Immunogen】:Recombinant protein of human RGR
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with RGR antibody diluted at 1:1000;Lane: rat spinal cord.