Anti-CFL2 Polyclonal Antibody
Cat: K005619P
Summary:
| 【Product name】：Anti-CFL2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1073 | 【Swiss Prot】：Q9Y281 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human CFL2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunofluorescence analysis of A549 cell using CFL2 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with CFL2 antibody diluted at 1:1000;Lane: A549 HeLa Raji NCI-H460 Mouse heart Mouse skeletal muscle Mouse kidney Rat brain.