Anti-STK4 Polyclonal Antibody
Cat: K005631P
Summary:
| 【Product name】：Anti-STK4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6789 | 【Swiss Prot】：Q13043 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IP,IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human STK4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Verified picture:
Western blot analysis with STK4 antibody diluted at 1:1000;Lane: U-87MG HepG2 HeLa MCF7 Mouse brain Mouse lung Mouse spleen Rat liver.
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using STK4 antibody at dilution of 1:100 (x100 lens,x200 lens).