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Anti-HMGCL Polyclonal Antibody
Cat: K005634P
Summary:
【Product name】:Anti-HMGCL Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3155 【Swiss Prot】:P35914
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human HMGCL
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with HMGCL antibody diluted at 1:1000;Lane: U-251MG SKOV3 BT-474 MCF7 Mouse liver Mouse kidney.
Immunohistochemistry of paraffin-embedded rat kidney using HMGCL antibody at dilution of 1:100 (x40 lens).