Anti-C8B Polyclonal Antibody - SAlexa Fluor 633
Cat: K005758P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-C8B Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：732 | 【Swiss Prot】：P07358 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human C8B | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
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