Anti-HLA-E Polyclonal Antibody - SAlexa Fluor 405
Cat: K005831P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-HLA-E Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3133 | 【Swiss Prot】：P13747 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human HLA-E | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Verified picture: