Anti-PER1 Polyclonal Antibody
Cat: K005847P
Summary:
| 【Product name】：Anti-PER1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5187 | 【Swiss Prot】：O15534 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human PER1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Verified picture:
Immunohistochemistry of paraffin-embedded human stomach using PER1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with PER1 antibody diluted at 1:1000;Lane: Mouse testis Rat testis Rat pancreas.
Immunohistochemistry of paraffin-embedded human colon with PER1 antibody diluted at 1:75.
Immunofluorescence analysis of U2OS cells using PER1 antibody diluted at 1:100.