Anti-UVRAG Polyclonal Antibody - RBITC
Cat: K005856P - RBITC
Summary:
| 【Product name】：Anti-UVRAG Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7405 | 【Swiss Prot】：Q9P2Y5 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human UVRAG | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
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