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Anti-EHMT1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K005888P - SAlexa Fluor 640
Summary:
【Product name】:Anti-EHMT1 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:79813 【Swiss Prot】:Q9H9B1
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:WB
【Immunogen】:Recombinant protein of human EHMT1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
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