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Anti-PHLPP1 Polyclonal Antibody
Cat: K006039P
Summary:
【Product name】:Anti-PHLPP1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:23239 【Swiss Prot】:O60346
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human PHLPP1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Verified picture:
Western blot analysis with PHLPP1 antibody diluted at 1:1000;Lane: HeLa SH-SY5Y Mouse testis Mouse brain Rat testis Rat brain.
Immunohistochemistry of paraffin-embedded mouse kidney with PHLPP1 antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using PHLPP1 antibody diluted at 1:100.