Anti-TIMM8A Polyclonal Antibody - SAlexa Fluor 568
Cat: K006059P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-TIMM8A Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1678 | 【Swiss Prot】：O60220 |
| 【Species reactivity】：Mouse,Human,Rat | |
| 【Tested applications】：IF,WB | |
| 【Immunogen】：Recombinant protein of human TIMM8A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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