下载
Anti-Phospho-MAP3K7-S412 Polyclonal Antibody - SAlexa Fluor 555
Cat: K006194P - SAlexa Fluor 555
Summary:
【Product name】:Anti-Phospho-MAP3K7-S412 Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:6885 【Swiss Prot】:O43318
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Verified picture: