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Anti-PRMT2 Polyclonal Antibody
Cat: K006344P
Summary:
【Product name】:Anti-PRMT2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3275 【Swiss Prot】:P55345
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human PRMT2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.
Verified picture:
Western blot analysis with PRMT2 antibody diluted at 1:1000;Lane: mouse lung.
Immunohistochemistry of paraffin-embedded human liver injury using PRMT2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cells using PRMT2 antibody.