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Anti-CTNNA1 Polyclonal Antibody - Cy5.5
Cat: K006689P - Cy5.5
Summary:
【Product name】:Anti-CTNNA1 Polyclonal Antibody - Cy5.5 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1495 【Swiss Prot】:P35221
【Species reactivity】:Mouse,Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CTNNA1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Catenin alpha-1?is a?protein?that in humans is encoded by the?CTNNA1?gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.
Verified picture: