Anti-DNMT3A Polyclonal Antibody - SAlexa Fluor 568
Cat: K006733P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-DNMT3A Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1788 | 【Swiss Prot】：Q9Y6K1 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：Recombinant protein of human DNMT3A | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture: