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Anti-OAS2 Polyclonal Antibody - SAlexa Fluor 488
Cat: K006804P - SAlexa Fluor 488
Summary:
【Product name】:Anti-OAS2 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4939 【Swiss Prot】:P29728
【Species reactivity】:Mouse,Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human OAS2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
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