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Anti-PAX8 Polyclonal Antibody
Cat: K006813P
Summary:
【Product name】:Anti-PAX8 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:7849 【Swiss Prot】:Q06710
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human PAX8
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.?
Verified picture:
Western blot analysis with PAX8 antibody diluted at 1:250;Lane: MCF7 Mouse brain.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with PAX8 antibody diluted at 1:35