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Anti-PEG10 Polyclonal Antibody - SAlexa Fluor 532
Cat: K006818P - SAlexa Fluor 532
Summary:
【Product name】:Anti-PEG10 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:23089 【Swiss Prot】:Q86TG7
【Species reactivity】:Human
【Tested applications】:WB
【Immunogen】:Recombinant protein of human PEG10
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
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